Health Outcomes of COVID-19 ICU Survivors
A Review Article
Abstract
Introduction: The COVID-19 pandemic has led to a significant number of patients requiring ICU admission. Survivors of COVID-19 who have been treated in the ICU may experience a decrease in their quality of life (QOL) due to physical, psychological, and social consequences. This review study aims to evaluate the QOL of ICU survivors of the COVID-19 pandemic. Methods: To conduct this review, a systematic literature search was performed using the PubMed, Scopus, and Cochrane Library databases. Studies published between January 2020 and July 2023 were included in this review. The search strategy included keywords such as COVID-19, Intensive Care Units, Survivors, Quality of Life, Outcome Measures. Results: The initial search identified 113 studies, of which 16 met the inclusion criteria and were included in this review. The QOL of ICU survivors of the COVID-19 pandemic was found to be significantly lower than that of the general population, with physical, psychological, and social impairments being the most commonly reported consequences. The use of rehabilitation interventions, such as early mobility and exercise, were found to improve QOL in ICU survivors of the COVID-19 pandemic. Conclusion: COVID-19 patients who require hospitalization and ICU admission may experience short-term and long-term physical, cognitive, emotional, and societal complications and effects after hospital discharge. These complications can significantly impact the patients' health-related quality of life, physical functioning, and psychological well-being.Kaye, Alan D., et al. "Economic impact of COVID-19 pandemic on healthcare facilities and systems: International perspectives." Best Practice & Research Clinical Anaesthesiology 35.3 (2021): 293-306.
Tarricone, Rosanna, and Carla Rognoni. "What can health systems learn from COVID-19?." European Heart Journal Supplements 22.Supplement_P (2020): P4-P8.
Haldane, Victoria, et al. "Health systems resilience in managing the COVID-19 pandemic: lessons from 28 countries." Nature Medicine 27.6 (2021): 964-980.
Musheyev, Benjamin, et al. "Characterizing non-critically ill COVID-19 survivors with and without in-hospital rehabilitation." Scientific reports 11.1 (2021): 21039.
Heesakkers, Hidde, et al. "Mental health symptoms in family members of COVID-19 ICU survivors 3 and 12 months after ICU admission: a multicentre prospective cohort study." Intensive Care Medicine 48.3 (2022): 322-331.
Sheehy, Lisa Mary. "Considerations for postacute rehabilitation for survivors of COVID-19." JMIR public health and surveillance 6.2 (2020): e19462.
Monti, Laura, et al. "COVID-19 pandemic in the intensive care unit: Psychological implications and interventions, a systematic review." World Journal of Psychiatry 13.4 (2023): 191.
Hayati, Hadi. "Pharmacotherapy analysis for hospitalized patients with COVID-19 (prescriptions, costs and outcomes)." Iranian Red Crescent Medical Journal (2023).
Nyasulu, Peter S., et al. "Clinical characteristics associated with mortality of COVID-19 patients admitted to an intensive care unit of a tertiary hospital in South Africa." PloS one 17.12 (2022): e0279565.
Kompaniyets, Lyudmyla, et al. "Body mass index and risk for COVID-19–related hospitalization, intensive care unit admission, invasive mechanical ventilation, and death—United States, March–December 2020." Morbidity and Mortality Weekly Report 70.10 (2021): 355.
Allenbach, Yves, et al. "Development of a multivariate prediction model of intensive care unit transfer or death: A French prospective cohort study of hospitalized COVID-19 patients." PloS one 15.10 (2020): e0240711.
Covino, Marcello, et al. "Predicting intensive care unit admission and death for COVID-19 patients in the emergency department using early warning scores." Resuscitation 156 (2020): 84-91.
Vlake, Johan H., et al. "Effect of intensive care unit-specific virtual reality (ICU-VR) to improve psychological well-being and quality of life in COVID-19 ICU survivors: a study protocol for a multicentre, randomized controlled trial." Trials 22.1 (2021): 1-12.
Turan, Zeynep, Mahir Topaloglu, and Ozden Ozyemisci Taskiran. "Is tele‐rehabilitation superior to home exercise program in COVID‐19 survivors following discharge from intensive care unit?‐a study protocol of a randomized controlled trial." Physiotherapy Research International 26.4 (2021): e1920.
Damico, V., et al. "Long-term consequences in Covid-19 and Non-Covid-19 patients survivors of critical illness. A descriptive study." Annali di Igiene, Medicina Preventiva e di Comunita 35.4 (2023).
Gamberini, Lorenzo, et al. "Quality of life of COVID-19 critically ill survivors after ICU discharge: 90 days follow-up." Quality of Life Research 30 (2021): 2805-2817.
Jiang, David H., and Rozalina G. McCoy. "Planning for the post-COVID syndrome: how payers can mitigate long-term complications of the pandemic." Journal of general internal medicine 35 (2020): 3036-3039.
Mitrani, Raul D., Nitika Dabas, and Jeffrey J. Goldberger. "COVID-19 cardiac injury: Implications for long-term surveillance and outcomes in survivors." Heart rhythm 17.11 (2020): 1984-1990.
Gamberini, Lorenzo, et al. "Health-related quality of life profiles, trajectories, persistent symptoms and pulmonary function one year after ICU discharge in invasively ventilated COVID-19 patients, a prospective follow-up study." Respiratory medicine 189 (2021): 106665.
González, Jessica, et al. "Pulmonary function and radiologic features in survivors of critical COVID-19: a 3-month prospective cohort." Chest 160.1 (2021): 187-198.
Cuerda, Cristina, et al. "Impact of COVID-19 in nutritional and functional status of survivors admitted in intensive care units during the first outbreak. Preliminary results of the NUTRICOVID study." Clinical Nutrition 41.12 (2022): 2934-2939.
Berends, K., et al. "Experiences of COVID-ICU-survivors: mixed-methods study of psychological consequences by written survey." Tijdschrift voor Psychiatrie 63.5 (2021): 324-330.
De Tanti, Antonio, et al. "Cognitive and psychological outcomes and follow-up in severely affected COVID-19 survivors admitted to a rehabilitation hospital." Neurological Sciences 44.5 (2023): 1481-1489.
Keijsers, Karen, et al. "Memory impairment and concentration problems in COVID‐19 survivors 8 weeks after non‐ICU hospitalization: A retrospective cohort study." Journal of Medical Virology 94.9 (2022): 4512-4517.
Likhvantsev, Valery, et al. "Six-month quality of life in COVID-19 intensive care unit survivors." Journal of Cardiothoracic and Vascular Anesthesia 36.7 (2022): 1949-1955.
Miori, Sara, et al. "Incidence, risk factors, and consequences of post-traumatic stress disorder symptoms in survivors of COVID-19-related ARDS." International journal of environmental research and public health 20.8 (2023): 5504.
Misak, Cheryl. "Life after the storm: Surviving COVID-19." Perspectives in Biology and Medicine 63.3 (2020): 494-501.
Monti, Giacomo, et al. "Two‐months quality of life of COVID‐19 invasively ventilated survivors; an Italian single‐center study." Acta Anaesthesiologica Scandinavica 65.7 (2021): 912-920.
Onrust, Marisa, et al. "Physical, social, mental and spiritual functioning of COVID-19 intensive care unit-survivors and their family members one year after intensive care unit-discharge: A prospective cohort study." Intensive and Critical Care Nursing 75 (2023): 103366.
Piras, Ilenia, et al. "Experiences, emotions, and health consequences among COVID-19 survivors after intensive care unit hospitalization." International journal of environmental research and public health 19.10 (2022): 6263.
Sutton-Smith, Lynsey, et al. "What are the long-term outcomes for New Zealand survivors of critical illness?." The New Zealand Medical Journal (Online) 134.1547 (2021): 121-126.
Files | ||
Issue | Vol 9 No 4 (2023) | |
Section | Review Article(s) | |
DOI | https://doi.org/10.18502/jppm.v9i4.14610 | |
Keywords | ||
Qualit of Life ICU Survivors COVID-19 Outcome |
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