Assessment of Health-related Quality of Life in Cancer Patitients Receiving Chemotherapy in Specialist Hospital, Jalingo, North Eastern of Nigeria
Abstract
Background: This study aimed to assess Health-Related Quality of Life (HRQoL) in cancer patients receiving chemotherapy in Specialist Hospital, Jalingo, North-Eastern Nigeria, in 2015. Methods: A cross-sectional study was conducted on 218 cancer patients selected by systematic random sampling method. The study data were collected using a modified European Organization for Research and Treatment of Cancer QoL Questionnaire (EORTC QLQ-C30 v. 3). Results: Out of the 218 participants, 42(18.8%) had between 1 to 4 chemotherapy cycles, while 86(39.4%) had 5 to 8 cycles and the remaining 91(41.7%) had 9 to 12 chemotherapy cycles. There was a significant relationship between HRQoL and the number of chemotherapy cycles received. Conclusion: Encouraging cancer patients to complete a chemotherapy course plays an essential role in the treatment outcome and the HRQoL in cancer patients undergoing chemotherapy.
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[25] Bottomley A, Flechtner H, Efficace F, Vanvoorden V, Coens C, Therasse P, et al. European Organisation for Research and Treatment of Cancer (EORTC) data center and quality of life group. Health related quality of life outcomes in cancer clinical trials. Eur J Cancer. 2005;41(12):1697-709. [DOI:10.1016/j.ejca.2005.05.007] [PMID]
[2] Ma X, Yu H. Global burden of cancer. Yale J Biol Med. 2006; 79(3-4):85-94. [PMID] [PMCID]
[3] Sidney S, Go AS, Rana JS. Transition From Heart Disease to Cancer as the Leading Cause of Death in the United States. Ann Intern Med. 2019; 171(3):225. [DOI:10.5888/pcd15.180151] [PMID] [PMCID]
[4] Jedy-Agba E, Curado MP, Ogunbiyi O, Oga E, Fabowale T, Igbinoba F, et al. Cancer incidence in Nigeria: A report from population-based cancer registries. Cancer Epidemiol. 2012; 36(5):e271-8 [DOI:10.1016/j.canep.2012.04.007] [PMID] [PMCID]
[5] Abdulkareem F. Epidemiology and incidences of common cancers in Nigeria. Cancer Reg & Epid Workshop April 2009. Available online at: http://ihvnigeria .org on March 11th 2018.
[6] World Health Organization (WHO). Programme on mental health. Geneve: World Health Organization; 1998. https://www.who.int/mental_health/evidence/who_qol_user_manual_98.pdf
[7] Boscolo–Rizzo P, Maronato F, Marchiori C, Gava A, Da Mosto MC. Long-term quality of life after total laryngectomy and postoperative radiotherapy versus concurrent chemoradiotherapy for laryngeal preservation. Laryngoscope. 2008; 118(2):300-6. [DOI:10.1097/MLG.0b013e31815a9ed3] [PMID]
[8] Gandek B, Sinclair SJ, Kosinski M, Ware Jr JE. Psychometric evaluation of the SF-36® health survey in medicare managed care. Health Care Financ Rev. 2004; 25(4):5-25. [PMCID] [PMID]
[9] Sarki A, Roni BL. This disease is “not for hospital”: myths and misconceptions about cancers in Northern Nigeria. J Glob Health. 2019; 3. [DOI:10.29392/joghr.3.e2019070]
[10] Dehkordi A, Heydarnejad MS, Fatehi D. Quality of life in cancer patients undergoing chemotherapy. Oman Med J. 2009; 24(3):204-7. [DOI:10.5001/omj.2009.40] [PMID] [PMCID]
[11] Heydarnejad MS, Hassanpour DA, Solati DK. Factors affecting quality of life in cancer patients undergoing chemotherapy. Afr Health Sci. 2011; 11(2):266-70. [PMID] [PMCID]
[12] Chen ML, Yu CT, Yang CH. Sleep disturbances and quality of life in lung cancer patients undergoing chemotherapy. Lung Cancer. 2008; 62(3):391-400. [DOI:10.1016/j.lungcan.2008.03.016] [PMID]
[13] Mystakidou K, Parpa E, Tsilika E, Pathiaki M, Patiraki E, Galanos A, et al. Sleep quality in advanced cancer patients. J Psychosom Res. 2007; 62(5):527-33. [DOI:10.1016/j.jpsychores.2006.11.008] [PMID]
[14] Fortner BV, Stepanski EJ, Wang SC, Kasprowicz S, Durrence HH. Sleep and quality of life in breast cancer patients. J Pain Symptom Manage. 2002; 24(5):471-80. [DOI:10.1016/S0885-3924(02)00500-6]
[15] Abdollahzadeh F, Sadat Aghahossini S, Rahmani A, Asvadi Kermani I. Quality of life in cancer patients and its related factors. J Caring Sci. 2012; 1(2):109-14. [DOI:10.5681/jcs.2012.016] [PMID] [PMCID]
[16] Thatcher N, Hopwood P, Anderson H. Improving quality of life in patients with non-small cell lung cancer: Research experience with gemcitabine. Eur J Cancer. 1997; 33:S8-13. [DOI:10.1016/S0959-
8049(96)00336-X]
[17] Rustøen T. Hope and quality of life, two central issues for cancer patients: A theoretical analysis. Cancer Nurs. 1995; 18(5):355-61. [DOI:10.1097/00002820-199510000-00004]
[18] Anand P, Kunnumakara AB, Sundaram C, Harikumar KB, Tharakan ST, Lai OS, et al. Cancer is a preventable disease that requires major lifestyle changes. Pharm Res. 2008; 25(9):2097-116.[DOI:10.1007/s11095-008-9661-9] [PMID] [PMCID]
[19] Gupta B, Kumar N, Johnson NW. Relationship of lifetime exposure to tobacco, alcohol and second hand tobacco smoke with upper aero-digestive tract cancers in India: A case-control study with a life-course perspective. APJCP. 2017; 18(2):347. [DOI:10.22034/APJCP.2017.18.2.347]
[20] Oh JK, Shin HR, Lim MK, Cho H, Kim DI, Jee Y, et al. Multiplicative synergistic risk of hepatocellular carcinoma development among hepatitis B and C co-infected subjects in HBV endemic area: A community-based cohort study. BMC Cancer. 2012; 12(1):1-8. [DOI:10.1186/1471-2407-12-452] [PMID] [PMCID]
[21] Doll R, Peto R. The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today. JNCI. 1981; 66(6):1192-308. [DOI:10.1093/jnci/66.6.1192]
[22] Taylor VH, Misra M, Mukherjee SD. Is red meat intake a risk factor for breast cancer among premenopausal women? Breast Cancer Res Treat. 2009; 117(1):1-8. [DOI:10.1007/s10549-009-0441-y] [PMID]
[23] Goodyear MD, Krleza-Jeric K, Lemmens T. The declaration of Helsinki. BMJ. 2007; 335(7621):624-5. [DOI:10.1136/bmj.39339.610000.BE] [PMID] [PMCID]
[24] Hürny C, Bernhard J, Castiglione-Gertsch M, Coates AS, Peterson HF, Gelber RD, et al. Impact of adjuvant therapy on quality of life in women with node-positive operable breast cancer. Lancet. 1996; 347(9011):1279-84. [DOI:10.1016/S0140-6736(96)90936-8]
[25] Bottomley A, Flechtner H, Efficace F, Vanvoorden V, Coens C, Therasse P, et al. European Organisation for Research and Treatment of Cancer (EORTC) data center and quality of life group. Health related quality of life outcomes in cancer clinical trials. Eur J Cancer. 2005;41(12):1697-709. [DOI:10.1016/j.ejca.2005.05.007] [PMID]
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| Issue | Vol 7 No 3/4 (2021) | |
| Section | Original Article(s) | |
| Keywords | ||
| Anticancer Quality of life Cycles of chemotherapy Nigeria | ||
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How to Cite
1.
Giwa A, Sabum C, Giwa H, Jamiu M. Assessment of Health-related Quality of Life in Cancer Patitients Receiving Chemotherapy in Specialist Hospital, Jalingo, North Eastern of Nigeria. JPPM. 2021;7(3/4):100-112.
