Tehran University of Medical Sciences Journal of Pharmacoeconomics and Pharmaceutical Management 2383-4498 1 1/2 2015 10 05 10 13 EN Fatemeh Soleymani National Committee on Rational Drug Use, Food and Drug Organization, Ministry of Health and Medical Education AND Department of Pharmacoeconomics and Pharmaceutical Management, Faculty of Pharmacy and Pharmaceutical Policy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Nikinaz Ashrafi Department of Pharmacoeconomics and Pharmaceutical Management, Faculty of Pharmacy and Pharmaceutical Policy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Arash Tehrani-banihashemi National Committee on Rational Drug Use, Food and Drug Organization, Ministry of Health and Medical Education AND Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran. Nooshin Mohammad-Hosseini National Committee on Rational Drug Use, Food and Drug Organization, Ministry of Health and Medical Education AND Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran. Fariba Ahmadizar National Committee on Rational Drug Use, Food and Drug Organization, Ministry of Health and Medical Education, Tehran, Iran. Kheirollah Gholami Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 05 2015 10 05 Background: Elderly are prone to many acute and chronic age-related diseases, which needed multiple medicine usage. Therefore, evaluation of medicine use pattern in this group is very important and a significant issue in public health system policy. Methods: This study was a cross-sectional household survey conducted in 20 clusters of Tehran. Each cluster consists of 40 households who had at least one person over the 60 years old. Different medicine items used by the individuals over 60 years old were asked and recorded by the interviewers. Results: A total of 1054 men and women over 60 years old were enrolled to the study. About 49.4% were male and 50.6% were female. About 69% of the study population used at least one medicine per day regularly, and 46.2% used to consume medicines as self-medication. Mean items per prescription were 3.57 for patients who used medicines regularly every day. The most frequent medicines used in this group were cardiovascular (68.6%) and central nervous system medicines (61.7%). Aspirin 80 mg, atenolol, and calcium-D were the most frequent medicines used regularly, but not daily. Acetaminophen 325 mg and acetaminophen codeine were the most frequent self-medications. Conclusion: Since elderly people may have multiple comorbidities, which require poly-pharmacy use. Also, due to the high prevalence of drug use without prescription among this group of people, which was about 46% in our study, it is crucial that physicians and other health care providers consider the risk of adverse drug reactions and drug interactions in each visit of the patient. https://jppm.tums.ac.ir/index.php/jppm/article/view/2 https://jppm.tums.ac.ir/index.php/jppm/article/download/2/2