Tehran University of Medical Sciences Journal of Pharmacoeconomics and Pharmaceutical Management 2383-4498 9 1 2023 04 29 27 38 Shahrbano Shafian Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Zahra Sharif Department of Pharmacology, School of Pharmacy, Alborz University of Medical Sciences, Karaj, Iran Leila Zarei Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. Mohammad Hadidi School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Kamran Lankarani Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran. 2021 12 19 2023 04 29 The Islamic Republic of Iran provided a national action plan against antimicrobial resistance (NAP/AMR) for 2016-2021. In this study, we have dealt with the background and Iran’s efforts in this way, compare Iran’s NAP/AMR with other international programs, represent efficient policy options, and the evaluation indicators of each purpose of Iran NAP/AMR. The indicators of each group are represented through the consensus of three academic researchers.    Finally, our assessment reveals that performing a constant observation is highly required for a prearranged NAP/AMR. The political parties and stakeholders should punctually receive interpretable feedbacks; also, it is very important to conduct periodical assessments with the purpose of perceiving the purpose feasibility and determining the dimensions that require advancements. https://jppm.tums.ac.ir/index.php/jppm/article/view/182